131953-10-1

Basic information

• Product Name: 2(3H)-Furanone, 3-(bromoacetyl)dihydro- (9CI)
• Synonyms: 2(3H)-Furanone, 3-(bromoacetyl)dihydro- (9CI)
• CAS NO: 131953-10-1
• Molecular Formula: C6H7BrO3
• Molecular Weight: 207.02198
• Product Categories: ACETYLHALIDE
• Mol File: 131953-10-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2(3H)-Furanone, 3-(bromoacetyl)dihydro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone, 3-(bromoacetyl)dihydro- (9CI)(131953-10-1)
• EPA Substance Registry System: 2(3H)-Furanone, 3-(bromoacetyl)dihydro- (9CI)(131953-10-1)

Safety Data

• Hazardous Substances Data: 131953-10-1(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 4360-91-2 α-carboxy-γ-butyrolactone 
• 79-37-8 oxalyl dichloride 
• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 

Downstream Products

• 156928-09-5 (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol 

Relevant articles and documents

Method For Preparing Hexahydrofuro-Furanol Derivative, Intermediate Thereof And Preparation Method Thereof

The invention relates to the field of pharmaceutical synthesis, in particular to a preparation method of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivatives and their intermediates. The preparation method is carried out starting from compound Formula A1. In the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivatives, the chirality was constructed by enzymatic method, and the products were prepared with high optical purity. The preparation method can be used to produce the key intermediates of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol of darunavir commercially, which is a very economical route suitable for industrial production.

Cephalosporin derivatives

β-Lactam compounds of the formula (Ia) including pharmaceutically acceptable salts and in vivo hydrolysable esters, processes for their preparation and their use as antibiotics: STR1 wherein R1 is hydrogen, methoxy or formamido; R2 i