131965-08-7

Basic information

• Product Name: 1-(1-benzofuran-5-yl)-2-[3-(dimethylamino)propoxy]ethanol
• CAS NO: 131965-08-7
• Molecular Formula: C₁₅H₂₁NO₃
• Molecular Weight: 263.3321
• Mol File: 131965-08-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 385.3°C at 760 mmHg
• Flash Point: 186.8°C
• Density: 1.127g/cm³
• Vapor Pressure: 1.26E-06mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 1-(1-benzofuran-5-yl)-2-[3-(dimethylamino)propoxy]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-benzofuran-5-yl)-2-[3-(dimethylamino)propoxy]ethanol(131965-08-7)
• EPA Substance Registry System: 1-(1-benzofuran-5-yl)-2-[3-(dimethylamino)propoxy]ethanol(131965-08-7)

Safety Data

• Hazardous Substances Data: 131965-08-7(Hazardous Substances Data)

Usage

General Description

1-(1-benzofuran-5-yl)-2-[3-(dimethylamino)propoxy]ethanol, also known as nefopam, is a synthetic chemical compound used primarily as an analgesic medication. It is a non-opioid painkiller that works by inhibiting the reuptake of serotonin and norepinephrine, two neurotransmitters involved in pain regulation. Nefopam is structurally related to the tricyclic antidepressants and is used to treat moderate to severe pain, such as postoperative pain or chronic musculoskeletal pain. It is also used as an adjunct therapy for the management of neuropathic pain. Nefopam is not widely available in some countries and is often considered a second-line medication due to its potential for side effects and contraindications.