1319727-19-9Relevant articles and documents
Pyrroles and indolizidines from deprotonated α-(alkylideneamino) nitriles
Schaefer, Ines,Opatz, Till
experimental part, p. 1691 - 1704 (2011/07/29)
Their ready availability from simple starting materials in only two synthetic steps and their versatility as building blocks for the construction of highly substituted amines and N-heterocycles renders α-(alkylideneamino) nitriles useful synthetic intermediates. Herein, short syntheses of tri- and tetrasubstituted pyrroles including the northern half of the HMG-CoA reductase inhibitor atorvastatin as well as an access to 3-substituted indolizidines will be described. Georg Thieme Verlag Stuttgart - New York.