131981-85-6Relevant academic research and scientific papers
Synthesis of β-fluoro-α,β-unsaturated esters and nitriles via a fluoro-Pummerer rearrangement
Krishnan,Sampson
, p. 5609 - 5612 (2007/10/02)
A 5-step synthesis of terminally unsaturated β-fluoro-α,β-unsaturated esters and nitriles 1 is described. Substantial amounts of a deoxygenative side reaction were observed during the key fluoro-Pummerer rearrangement step in the routes leading to the nitriles 1c and 1d.
