13199-54-7

Basic information

• Product Name: 1,4-Dimethoxy-2,3,5,6-tetramethylbenzene
• Synonyms: 1,4-Dimethoxy-2,3,5,6-tetramethylbenzene;Dimethoxydurene
• CAS NO: 13199-54-7
• Molecular Formula: C₁₂H₁₈O₂
• Molecular Weight: 194.27
• Mol File: 13199-54-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 112-115 °C
• Boiling Point: 283.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.1525 g/cm3
• CAS DataBase Reference: 1,4-Dimethoxy-2,3,5,6-tetramethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dimethoxy-2,3,5,6-tetramethylbenzene(13199-54-7)
• EPA Substance Registry System: 1,4-Dimethoxy-2,3,5,6-tetramethylbenzene(13199-54-7)

Safety Data

• Hazardous Substances Data: 13199-54-7(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Sweet, floral

Uses

Fragrance ingredient in perfumes and personal care products
Solvent
Intermediate in the synthesis of other organic compounds

Toxicity

Relatively non-toxic

Acute toxicity

Low potential

Skin irritation

Low potential

Skin sensitization

Low potential

Precautions

Prolonged or repeated exposure to high concentrations may cause harmful effects

Safety procedures

Handle with caution and in accordance with proper safety procedures

Upstream product

• 527-17-3 Duroquinone 
• 77-78-1 dimethyl sulfate 
• 205862-10-8 2,3-bis(bromomethyl)-1,4-dimethoxy-5,6-dimethylbenzene 
• 60-29-7 diethyl ether 
• 54757-17-4 1-chloromethyl-2,5-dimethoxy-3,4,6-trimethyl-benzene 
• 527-18-4 Durohydroquinone 

Downstream Products

• 527-17-3 Duroquinone 
• 104157-20-2 1,2,4,5-tetrakis(bromomethyl)-3,6-dimethoxybenzene 
• 99622-28-3 2,2'-pentamethylenebis(3,5,6-trimethyl-1,4-benzoquinone) 
• 1132810-78-6 (S)-1-benzyloxy-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-methyl-butan-2-ol 
• 1132810-77-5 (R)-1-benzyloxy-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-methyl-butan-2-ol 
• 85148-25-0 (S)-4-(2',5'-dimethoxy-3',4',6'-trimethylphenyl)-2-methyl-1,2-butanediol 
• 59-02-9 Tocopherol 
• 96203-94-0 (S)-4-(2,5-Dimethoxy-3,4,6-trimethylphenyl)-2-methyl-1-(4-tolylsulfonyloxy)butan-2-ol 
• 96203-95-1 (S)-4-(2,5-Dimethoxy-3,4,6-trimethylphenyl)-1,2-epoxy-2-methylbutan 
• 91418-95-0 (3R,7R,11R)-1-(2',5'-dimethoxy-3',4',6'-trimethylphenyl)-3,7,11,15-tetramethyl-hexadecan-3-ol 
• 7559-04-8 2-[(3R,7R,11R)-3-hydroxy-3,7,11,15-tetramethylhexadecyl]-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione 

Relevant articles and documents

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Oxidative Dealkylation of Hydroquinone Ethers with Nitrogen Dioxide in the Convenient Preparation of Quinones

Various Hydroquinone dialkyl ethers (R2Q) are effectively converted by nitrogen dioxide into the corresponding quinone (Q) and alkyl nitrite (RONO) in dichloromethane at room temperature or below.The preparative procedure for the isolation of crystalline quinones in quantitative yield merely involves the convenient removal of the low boiling solvent in vacuo.Isotopic labelling studies demonstrate that the oxidative dealkylation proceeds via alkoxy scission of the labile cation radical (R2Q-cation radical) formed via the oxidation of the hydroquinone ether by nitrogen dioxide ( as the disproportionated ion pair NO+NO3-).The electron-transfer mechanism is confirmed by the spectral observation of R2Q-cation radical (identified by the isolation of the crystalline salt R2Q-cation radical-SbCl6-) and its rapid conversion into quinone and alkyl nitrite by combination with nitrate (NO3-) and nitric oxide (NO).

Repetitive Diels-Alder Reactions for the Growth of Linear Polyacenequinoid Derivatives

Starting from 2,3,5,6-tetramethylidene-7-oxanorbornane, repetitive quinone Diels-Alder/oxidation reactions produced a series of epoxypolyacenequinones with up to eleven linearly annulated rings.Epoxide ring opening-oxidation gave polyacenequinones with se