131992-92-2

Downstream Products

• 627096-93-9 ethyl 2-[3-[N-(4-chlorobenzyl)aminomethyl]phenoxy]-2-methylpropionate 
• 1393371-47-5 2-(3-(benzo[d]thiazol-2-yl)phenoxy)-2-methylpropanoic acid 
• 1393371-46-4 2-(3-(1H-benzo[d]imidazol-2-yl)phenoxy)-2-methylpropanoic acid 
• 1310698-68-0 Ethyl 2-[3-({3-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propylamino}methyl)phenoxy]-2-methylpropanoate 
• 851508-11-7 ethyl (E)-2-methyl-2-(3-(2-nitrovinyl)phenoxy)propanoate 

Relevant academic research and scientific papers

Novel Compounds

The present invention provides compounds of formula (I): wherein Ra, Rb, Rc, R1, R2, R3, X1, Y1, Z1, A, n and m are as defined in the specification, and pharmaceutically acceptable salts thereof, as well as processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

1,2-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND PHARMACEUTICAL COMPOSITIONS THEREOF

The invention relates to compounds, pharmaceutical compositions and methods of using compounds of the general formula (I), or its pharmaceutically acceptable salt or ester, wherein the substituents are defined in the application.

Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof

The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising same, their therapeutic uses, in particular for treating cerebral ischemia. The invention also concerns a method for preparing said derivatives.

Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives, preparation and uses thereof

The invention concerns compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives designed for therapeutic use. The inventive compositions are useful in particular for preventing or treating cardiovascular diseases, syndrome X, la restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders related to oxidative stress, for preventing or treating the effects of ageing in general and for example skin ageing, in particular in the field of cosmetics (occurrence of wrinkles and the like).

Phenyl derivatives, their manufacture and use as pharmaceutical agents

This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.