132-32-1 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 132-32-1 differently. You can refer to the following data:
1. brown fine crystalline powder and chunks
2. 3-Amino-9-ethylcarbazole is a brown or tan, crystalline compound.
Uses
Different sources of media describe the Uses of 132-32-1 differently. You can refer to the following data:
1. 3-Amino-9-ethylcarbazole (AEC) has been used as a chromogen in immunohistochemistry to visualize the cells. It has also been used as a substrate in enzyme-linked immune absorbent spot (ELISpot).
2. 3-Amino-9-ethylcarbazole has been used to visualize the bound primary antibody by using a streptavidin method. It has also been used in visualizing tissue sections from tumour samples.
Definition
A hydrochloride salt
and free amine solid compound.
General Description
Tan powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
3-Amino-9-ethylcarbazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.
Hazard
Questionable carcinogen; poison.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition 3-Amino-9-ethylcarbazole emits toxic fumes.
Fire Hazard
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Safety Profile
Suspected carcinogen with experimental carcinogenic data. Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx,.
Potential Exposure
Plant workers engaged in the manufacture of this compound and its use in pigment manufacture. Laboratory workers using this material in colorimetric enzyme assays and as a biological stain
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Incompatibilities
3-Amino-9-ethylcarbazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.
Waste Disposal
Incinerator equipped with a scrubber or thermal unit to reduce nitrogen oxides emissions.
Check Digit Verification of cas no
The CAS Registry Mumber 132-32-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 2 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 132-32:
(5*1)+(4*3)+(3*2)+(2*3)+(1*2)=31
31 % 10 = 1
So 132-32-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3
132-32-1Relevant articles and documents
A carbazole-based turn-on fluorescent probe for the detection of hydrazine in aqueous solution
Wang, Wei-Dong,Hu, Yang,Li, Qiao,Hu, Sheng-Li
, p. 206 - 211 (2018)
A carbazole-based fluorescent probe, 2-(9-ethyl-9H-carbazol-3-yl) isoindoline-1,3-dione, with a low detection limit (2.673 × 10?6 M) for the detection of hydrazine is designed and synthesized based on Gabriel reaction. The probe responds selectively to hydrazine over other amino compounds with marked fluorescence enhancement. Moreover, test paper experiments indicated its great potential in the environment monitoring of hydrazine in aqueous solution.
Introduction of a luminescent sensor for tracking trace levels of hydrazine in insect pollinated cropland flowers
Chattopadhyay, Ansuman,Das, Sujoy,Rissanen, Kari,Saha, Shrabani,Sahoo, Prithidipa,Sarkar, Olivia
supporting information, p. 17095 - 17100 (2021/10/04)
In recent years the excessive use of hydazine containing chemical pesticides and insecticides in farming practices is well pronounced, which directly or indirectly impart a great threat towards the total environment. Considering the above fact we are motivated to introduce a new, efficient and simple chemodosimeter (NCD) based on a carbazole-naphthalimide framework to recognize and estimate the mutagenic hydrazine within several affected cropland flowers. ProbeNCDcan detect hydrazine in a nanomolar range (65 nM or 2 ppb) in the presence of other metal ions, anions and amines, which gives it not only great potential but also makes it selective and sensitive. The sensing mechanism is confirmed by UV-vis, emission, and mass spectroscopy, and computational studies. We have successfully characterized probeNCDby1H and13C NMR and mass spectrometry as well as by single crystal analysis.
Use for RL intermediate condensation product synthesis process (by machine translation)
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Paragraph 0017; 0018, (2017/08/29)
The present invention discloses a use for RL intermediate condensation product synthesis process, the process comprises the steps of: carbazole alkylation N - ethyl carbazole made, by nitration, reduction to generate a 3 - amino - N - ethyl carbazole, then in the organic solvent in the condensation reaction, use for intermediate condensate obtained RL; in this invention the condensation reaction using an alcohol as a solvent to replace the traditional O-chlorobenzene, improves the 3 - amino - N - ethyl carbazole conversion rate, and improves the use for RL crude purity and yield, and the process is stable, simple operation, high safety factor. (by machine translation)
