132004-39-8

Basic information

• Product Name: 3-(carboxymethyl)-6-chloro-1H-indole-2-carboxylic acid
• Synonyms: 1H-indole-3-acetic acid, 2-carboxy-6-chloro-
• CAS NO: 132004-39-8
• Molecular Formula: C₁₁H₈ClNO₄
• Molecular Weight: 253.6385
• Mol File: 132004-39-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 562.9°C at 760 mmHg
• Flash Point: 294.2°C
• Density: 1.649g/cm³
• Vapor Pressure: 1.65E-13mmHg at 25°C
• Refractive Index: 1.731
• CAS DataBase Reference: 3-(carboxymethyl)-6-chloro-1H-indole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(carboxymethyl)-6-chloro-1H-indole-2-carboxylic acid(132004-39-8)
• EPA Substance Registry System: 3-(carboxymethyl)-6-chloro-1H-indole-2-carboxylic acid(132004-39-8)

Safety Data

• Hazardous Substances Data: 132004-39-8(Hazardous Substances Data)

Upstream product

• 132623-45-1 2-(3-chloro-phenylhydrazono)-glutaric acid diethyl ester 
• 1501-06-0 diethyl 2-acetylglutarate 
• 132623-15-5 (2-ethoxycarbonyl-6-chloro-indol-3-yl)-acetic acid ethyl ester 

Downstream Products

• 132623-16-6 ethyl 2-carboxy-6-chloro-3-indoleacetate 
• 132623-32-6 6-Chloro-3-(phenethylcarbamoyl-methyl)-1H-indole-2-carboxylic acid 

Relevant articles and documents

Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders

Compositions containing certain indole-2-carboxylate compounds and derivatives are described as being therapeutically effective in treatment of CNS disorders resulting from neurotoxic damage or neurodegenerative diseases, particularly those CNS disorders

Excitatory amino acid antagonists

The present invention is directed to the discovery of a new use for a group of known 2-carboxylic indole derivatives. The compounds are excitatory amino acid antagonists.