132016-80-9

Upstream product

• 81445-44-5 (S)-2-(benzyloxy)propanal 
• 122553-22-4 (Z)-(R)-1,3-bis(triethylsilyloxy)-1-methoxy-1-butene 

Downstream Products

• 141964-96-7 (2S,3S,4S)-4-Benzyloxy-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3-hydroxy-pentanoic acid methoxy-amide 
• 141993-95-5 (3S,4R)-4-(1-Benzyloxy-ethyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-methoxy-azetidin-2-one 
• 141964-94-5 (2S,3S,4S)-4-Benzyloxy-2-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3-hydroxy-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Unique Stereocontrol in Lanthanide(III)-Catalyzed Aldol Reactions with the Ketene Silyl Acetal of Methyl (R)-3-Hydroxybutanoate

The Eu(III)-catalyzed reaction of α-benzyloxyaldehydes with the (R)-3-hydroxybutanoate-derived ketene silyl acetal is shown to provide a higher level of both "anti" diastereofacial seletion and rather unusual diastereoselection, compared with the conventi

Diastereofacial Selection in Titanium Tetrachloride-Promoted Aldol Reactions with the Silyl Ketene Acetal of Methyl (R)-3-Hydroxybutanoate

The title reaction is shown to exhibit a high level of "anti" diastereofacial selection, in contrast to the "syn" selection observed for the reaction with the dilithium enolate of the chiral ester.Mechanistic grounds for the "anti" stereoselection are dis