1320269-89-3Relevant academic research and scientific papers
Synthesis of 4′-ethynyl-2′-deoxy-4′-thioribonucleosides and discovery of a highly potent and less toxic NRTI
Haraguchi, Kazuhiro,Shimada, Hisashi,Kimura, Keigo,Akutsu, Genta,Tanaka, Hiromichi,Abe, Hiroshi,Hamasaki, Takayuki,Baba, Masanori,Gullen, Elizabeth A.,Dutschman, Ginger E.,Cheng, Yung-Chi,Balzarini, Jan
supporting information; experimental part, p. 692 - 697 (2011/12/02)
The synthesis of 4′-ethynyl-2′-deoxy-4′- thioribonucleosides was carried out utilizing an electrophilic glycosidation in which 4-ethynyl-4-thiofuranoid glycal 16 served as a glycosyl donor. Electrophilic glycosidation between 16 and the silylated nucleoba
