132030-64-9Relevant academic research and scientific papers
On Triazoles XXIII. The Reaction of 5-Amino-1,2,4-triazoles with Thiacyclohexane β-Oxo Esters
Reiter, Jozsef,Esses-Reiter, Klara
, p. 561 - 571 (2007/10/02)
Six novel isomeric ring systems, namely the thiopyrano-1,2,4-triazolopyrimidine, the thiopyrano-1,2,4-triazolopyrimidine, the thiopyrano-1,2,4-triazolopyrimidine, the thiopyrano-1,2,4-triazolopyrimidine, the thiopyrano-1,2,4-triazolopyrimidine and the thiopyrano-1,2,4-triazolopyrimidine were synthesized.Spectroscopical evidence was given for the structure of compounds obtained.
Novel triazolo-pyrimidine derivatives
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, (2008/06/13)
This invention relates to novel triazolopyrimidine derivatives of formulae (Ia) and (Ib), STR1 wherein Q represents hydrogen, a heterocyclic group optionally substituted by a C1-4 alkyl group and containing one or more oxygen and/or nitrogen atoms or a group of formula --SR1 wherein R1 is alkyl or aralkyl, or a group of formula --NR2 R3 wherein R2 and R3 are independently hydrogen, alkyl, alkenyl, cycloalkyl, aralkyl, aryl or a heterocyclic group, m and n are independently 0, 1, 2, 3 or 4, with the provision that if m stands for 0, then n is different from 0, and if both n and m are 1 or m stands for 0 and n is 2, the Q is different from methylthio or morpholino group, their mixtures or pharmaceutically acceptable salts. Furthermore, the invention relates to a process for preparing these compounds. The compounds of formulae (Ia) and (Ib) are able to inhibit the ptosis caused by tetrabenazine and they have analgetic activity.
