132059-52-0

Basic information

• Product Name: 3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE
• Synonyms: 3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE;BMX 2;2(5H)-Furanone,3-chloro-4-(dibromomethyl)-5-hydroxy-
• CAS NO: 132059-52-0
• Molecular Formula: C₅H₃Br₂ClO₃
• Molecular Weight: 306.33652
• Product Categories: Heterocycles;Mutagenesis Research Chemicals;Heterocycles, Mutagenesis Research Chemicals
• Mol File: 132059-52-0.mol

Chemical Properties

• Boiling Point: 416.4°Cat760mmHg
• Flash Point: 205.6°C
• Appearance: /
• Density: 2.41g/cm³
• Vapor Pressure: 1.13E-08mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly)
• PKA: 8.67±0.60(Predicted)
• CAS DataBase Reference: 3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE(132059-52-0)
• EPA Substance Registry System: 3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE(132059-52-0)

Safety Data

• Hazardous Substances Data: 132059-52-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE is used as a chemical compound in research for its mutagenic properties and potential carcinogenic effects. It aids in understanding the impact of micropollutants in drinking water and their effects on human health.
Used in Environmental Studies:
In environmental studies, 3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE is used as a reference compound to analyze and monitor the presence of harmful micropollutants in water sources. This helps in developing strategies for water purification and ensuring the safety of drinking water supplies.
Used in Pharmaceutical Development:
Although 3-CHLORO-4-(DIBROMOMETHYL)-5-HYDROXY-2(5H)-FURANONE is carcinogenic, its study can contribute to the development of pharmaceuticals and treatments targeting specific types of cancer. Understanding its properties and effects can lead to the discovery of new drugs or therapies that counteract or mitigate its harmful effects.

InChI:InChI=1/C5H3Br2ClO3/c6-3(7)1-2(8)5(10)11-4(1)9/h3-4,9H

Upstream product

• 77439-76-0 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone 

Relevant articles and documents

A simple synthesis of brominated analogues of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)

Three brominated analogues of the highly mutagenic drinking water micropollutant 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) have been synthesized from MX by halogen exchange reaction.

Improved synthesis of three brominated analogues of the potent environmental mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)

The synthesis of three brominated analogues of the environmental mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), namely, 3-chloro- 4-(bromochloromethyl)-5-hydroxy-2(5H)-furanone (BMX-1), 3-chloro-4- (dibromomethyl)-5-hydroxy-2(5H)-furanone (BMX-2) and 3-bromo-4- (dibromomethyl)-5-hydroxy-2(5H)-furanone (BMX-3), by employing a simple procedure from a common precursor, is described. (C) 2000 Elsevier Science Ltd.

Brominated analogs of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone: Preparation of 3-chloro-4-(bromochloromethyl)-5-hydroxy-2(5h)-furanone and mutagenicity studies

The brominated hydroxyfuranone structurally related to the potent mutagen MX, namely 3-chloro-4-(bromochloromethyl)-5-hydroxy-2(5H)-furanone (BMX-1), has been synthesized and characterized. The mutagenic activity of this bromohydroxyfuranone together with