132065-49-7

Upstream product

• 117248-23-4 (3RS,4S)-4-amino-6-methylhept-1-en-3-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 107599-94-0 3-hydroxy-6-methyl-4(S)-<(triphenylmethyl)amino>-1-heptene 
• 132065-46-4 (3RS,4S)-6-methyl-4-(p-tolylsulfonylamino)hept-1-en-3-ol 
• 132065-47-5 (2RS,4S,5RS)-4-isobutyl-2-phenylselenanylmethyl-3-(p-tolylsulfonyl)-5-vinyloxazolidine 
• 132065-55-5 C₂₃H₂₉NO₄SSe 

Relevant academic research and scientific papers

New Synthetic Methodology for the Synthesis of 7-Substituted Tetrahydroazepin-2-ones

The Claisen rearrangement of the vinyl substituted ketene aminals 2 (R = CH2CHMe2, CH2OSit-BuMe2) which were generated in situ by selenoxide elimination of the aminal precursors 3 in the presence of 1,8-diazabicycloundec-7-ene (DBU) furnished the enantiomerically pure 7-substituted tetrahydroazepin-2-ones 1.

Synthesis Of Homochiral Unsaturated Seven-Membered Lactams

The Claisen rearrangement of the vinyl substituted ketene aminals 6 which were generated in situ by selenoxide elimination of the aminal precursors 5 in the presence of 1,8-diazabicycloundec-7-ene (DBU) gave the homochiral unsaturated seven-membere