13207-63-1 Usage
Uses
Used in Pharmaceutical Industry:
5-iodo-8-quinolinol is used as an antiprotozoal and amoebicide medication for the treatment of infections caused by protozoa and other parasitic organisms. It is particularly effective against amoebiasis, an intestinal infection caused by the parasite Entamoeba histolytica.
Used in Public Health:
5-iodo-8-quinolinol is used as an essential medicine by the World Health Organization and is listed on its Model List of Essential Medicines. It is recognized for its effectiveness in treating parasitic infections and is included in various national essential medicines lists, contributing to public health efforts to combat these infections.
Used in Medical Treatment:
5-iodo-8-quinolinol is used as a therapeutic agent in the treatment of patients suffering from infections caused by protozoa and other parasitic organisms. Its effectiveness in treating amoebiasis makes it a valuable component in the medical arsenal against such infections.
Used in Research and Development:
5-iodo-8-quinolinol serves as a subject of research and development in the field of pharmaceuticals and medicine. Its mechanism of action and potential applications in treating other parasitic infections are areas of ongoing study, with the aim of expanding its use and improving treatment options for patients.
Used in Drug Formulation:
5-iodo-8-quinolinol is used in the formulation of various pharmaceutical products, such as tablets and oral solutions, for the treatment of protozoal and parasitic infections. Its well-tolerated nature and effectiveness make it a suitable component in these formulations, ensuring patient compliance and therapeutic success.
Check Digit Verification of cas no
The CAS Registry Mumber 13207-63-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,2,0 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13207-63:
(7*1)+(6*3)+(5*2)+(4*0)+(3*7)+(2*6)+(1*3)=71
71 % 10 = 1
So 13207-63-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H6INO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H
13207-63-1Relevant academic research and scientific papers
PURIFICATION TAGS OF SYNTHETIC PEPTIDES AND PROTEINS
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Paragraph 0041; 0042, (2013/08/28)
The present invention relates to a series of compounds useful for effecting purification, in particular for use in purification of synthetic peptides and proteins. The compounds of the invention are particularly efficient at securely anchoring peptides or
Palladium-catalysed reactions of 8-hydroxy- and 8-benzyloxy-5,7- diiodoquinoline under aminocarbonylation conditions
Takács, Attila,Szilágyi, Antal,ács, Péter,Márk, László,Peixoto, Andreia F.,Pereira, Mariette M.,Kollár, László
experimental part, p. 2402 - 2406 (2011/04/26)
Various 5-carboxamido-7-iodo-8-benzyloxyquinolines were synthesised via selective aminocarbonylation of 5,7-diiodo-8-benzyloxyquinoline in the presence of 'in situ' generated palladium(0) catalysts. Under similar conditions (50 °C, 80 bar CO), 5,7-bis(N-tert-butyl-glyoxylamido)-8-hydroxyquinoline was obtained using tert-butylamine as N-nucleophile. The unprotected 5,7-diiodo-8-hydroxyquinoline underwent dehydroiodination resulting in 8-hydroxyquinoline as the major product.
