132073-83-7

Basic information

• Product Name: (S)-morpholin-2-ylmethanol
• Synonyms: (S)-morpholin-2-ylmethanol;(S)-2-morpholinemethanol;(S)-morpholin-2-ylmethanol hydrochloride;2-MorpholineMethanol, (2S)-;(S)-Morpholin-2-ylMethanol-HCl;(S)-Morpholine-2-methanol;(2S)-Morpholin-2-ylMethanol;(2S)-2-Morpholinemethanol
• CAS NO: 132073-83-7
• Molecular Formula: C₅H₁₁NO₂
• Molecular Weight: 117.14634
• Mol File: 132073-83-7.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-morpholin-2-ylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-morpholin-2-ylmethanol(132073-83-7)
• EPA Substance Registry System: (S)-morpholin-2-ylmethanol(132073-83-7)

Safety Data

• Hazardous Substances Data: 132073-83-7(Hazardous Substances Data)

Usage

General Description

(S)-morpholin-2-ylmethanol is a novel chemical compound characterized by the presence of a morpholine group and a methanol group. Morpholine is an organic chemical compound which has a six-membered ring containing four carbon atoms, one oxygen atom and one nitrogen atom, and methanol, commonly known as wood alcohol, is the simplest alcohol, being only a methyl group linked to a hydroxyl group. Not much information is available about its specific properties or applications due to its novelty. However, both morpholine and methanol are versatile in their usage, being involved in diverse fields ranging from solvents to chemical synthesis, which may suggest potential uses for this compound.

InChI:InChI=1S/C5H11NO2.ClH/c7-4-5-3-6-1-2-8-5;/h5-7H,1-4H2;1H/t5-;/m0./s1

Upstream product

• 135065-76-8 tert-butyl (2S)-2-(hydroxymethyl)morpholine-4-carboxylate 
• 135065-72-4 (S)-N-benzyl-3-chloroacetamidopropane-1,2-diol 
• 148638-78-2 (S)-4-Benzyl-6-hydroxymethyl-morpholin-3-one 
• 205242-65-5 (S)-4-Benzyl-6-benzyloxymethyl-morpholin-3-one 
• 847805-29-2 (-)-2-chloro-N-((S)-2,3-dihydroxypropyl)acetamide 
• 847805-30-5 (6S)-6-(hydroxymethyl)morpholin-3-one 
• 205242-66-6 (2S)-4-(phenylmethyl)-2-{[(phenylmethyl)oxy]methyl}morpholine 
• 132073-82-6 (S)-4-Benzyl-2-(hydroxymethyl)morpholine 
• 1313584-92-7 (S)-2-(hydroxymethyl)morpholine hydrochloride 
• 148638-77-1 N-Benzyl-2-chloro-N-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-acetamide 

Downstream Products

• 2227425-05-8 (S)-3-chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile 
• 661470-52-6 (S)-2-(phenoxymethyl)morpholine 
• 919286-71-8 tert-butyl (2S)-2-(bromomethyl)-4-morpholinecarboxylate 
• 1137478-34-2 (R)-tert-butyl 2-((2-(5-cyanopyrazin-2-ylamino)-5-(4-methoxyphenyl)pyridin-4-ylamino)methyl)morpholine-4-carboxylate 
• 1137478-37-5 (S)-tert-butyl 2-((2-(5-cyanopyrazin-2-ylamino)-5-(4-methoxyphenyl)pyridin-4-ylamino)methyl)morpholine-4-carboxylate 
• 1137478-38-6 (R)-5-((5-(4-methoxyphenyl)-4-((morpholin-2-ylmethyl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile 
• 1168103-91-0 (S)-5-((5-(4-methoxyphenyl)-4-((morpholin-2-ylmethyl)amino)pyridin-2-yl)amino)pyrazine-2-carbonitrile 
• 1137478-31-9 (R)-tert-butyl 2-((2-chloro-5-(4-methoxyphenyl)pyridin-4-ylamino)methyl)morpholine-4-carboxylate 
• 1137478-36-4 (S)-tert-butyl 2-((2-chloro-5-(4-methoxyphenyl)pyridin-4-ylamino)methyl)morpholine-4-carboxylate 

Relevant articles and documents

Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER

A series of reboxetine analogs was synthesized and evaluated for in vitro binding as racemic mixtures. The best candidate (INER) was synthesized as the optically pure (S,S) enantiomer, labeled with iodine-123 and its in vivo binding determined by SPECT im

Novel Hydrazinone-substituted Pyrimidine Derivatives and Use Thereof

The present invention relates to a pyrimidine derivative substituted with novel hydrazine or a pharmaceutically acceptable salt thereof, and to a pharmaceutical composition for inhibiting c-Met tyrosine kinase activity and to a pharmaceutical composition for preventing or treating hyperproliferative disorders, which comprise same as an active ingredient. The present invention can be effectively used as a treatment agent for various hyperproliferative disorders related to excessive cell proliferation and growth caused by abnormal kinase activity, such as cancer, psoriasis, rheumatoid arthritis, and diabetic retinopathy by efficiently inhibiting c-Met tyrosine kinase activity.

Discovery of substituted 6-pheny-3H-pyridazin-3-one derivatives as novel c-Met kinase inhibitors

We report a series of phenyl substituted pyridazin-3-ones substituted with morpholino-pyrimidines. The SAR of the phenyl was explored and their c-Met kinase and cell-based inhibitory activity toward c-Met driven cell lines were evaluated. Described herein