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Lissoclinolide, also known as Tetrenolin, is a small non-nitrogenous lactone derived from the marine ascidian Lissoclinum patella. It is characterized by its potent in vitro antitumor activities and antibacterial properties, making it a valuable compound for pharmaceutical and medical applications.

132074-82-9

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132074-82-9 Usage

Uses

Used in Anticancer Applications:
Lissoclinolide is used as an anticancer agent for its in vitro antitumor activities. It demonstrates potential in targeting and inhibiting the growth of cancer cells, making it a promising candidate for further research and development in oncology.
Used in Antibacterial Applications:
Lissoclinolide is used as an antibacterial agent due to its ability to combat bacterial infections. Its potent antimicrobial properties can be harnessed to develop new treatments for various bacterial diseases, contributing to the fight against antibiotic resistance.
Used in Pharmaceutical Industry:
Lissoclinolide is used as a key compound in the pharmaceutical industry for its potential applications in developing new drugs targeting cancer and bacterial infections. Its unique properties and mechanisms of action offer opportunities for innovation in drug discovery and design.
Used in Marine Biotechnology:
Lissoclinolide is used as a bioactive molecule in marine biotechnology, where it can be further studied and utilized for the development of novel therapeutics and pharmaceutical products derived from marine organisms. Its isolation from the marine ascidian Lissoclinum patella highlights the potential of marine biodiversity for discovering new bioactive compounds with medicinal value.

Check Digit Verification of cas no

The CAS Registry Mumber 132074-82-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,0,7 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 132074-82:
(8*1)+(7*3)+(6*2)+(5*0)+(4*7)+(3*4)+(2*8)+(1*2)=99
99 % 10 = 9
So 132074-82-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O4/c12-6-2-1-5-10-8-9(4-3-7-13)11(14)15-10/h1-5,8,12-13H,6-7H2/b2-1+,4-3-,10-5+

132074-82-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (5E)-5-[(E)-4-hydroxybut-2-enylidene]-3-[(Z)-3-hydroxyprop-1-enyl]furan-2-one

1.2 Other means of identification

Product number -
Other names Lissoclinolide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132074-82-9 SDS

132074-82-9Upstream product

132074-82-9Downstream Products

132074-82-9Related news

A highly efficient and selective synthesis of lissoclinolide (cas 132074-82-9) featuring hydrogen transfer hydrozirconation,trans-selective Pd-catalyzed cross coupling of alkenylzirconiums with 1,1-dibromoalkenes and Ag-catalyzed lactonization providing(Z)-γ-alkylidenebutenolides07/30/2019

An antibiotic lissoclinolide has been synthesized from propargyl alcohol in 9 steps and in 32% overall yieldvia (i) hydrogen transfer hydrozirconation of TBS-protected propargyl alcohol withi-BuZrCp2Cl, (ii) Pd-catalyzedtrans-selective cross coupling of the hydrozirconation product with a key 1,...detailed

Stereocontrolled synthesis of lissoclinolide (cas 132074-82-9) by sequential transition metal-catalyzed lactonization/cross-coupling reactions07/29/2019

Lissoclinolide, 1, which is an antibiotic butenolide isolated from a Tuncate, has been synthesized stereoselectively by a reaction sequence in which the Ag(I)-catalyzed lactonization of (2E,6E)-2-bromo-8-hydroxy-2,6-octadien-4-ynoic acid, (E,E)-13, and the Pd/Cu-catalyzed cross-coupling reaction...detailed

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