13209-36-4Relevant academic research and scientific papers
K2S2O8-Mediated Synthesis of Highly Functionalized Pyrroles via Oxidative Self-Dimerization of N-Propargylamines
Behera, Bipin Kumar,Sahu, Archana Kumari,Devi, Ngangbam Renubala,Saikia, Anil K.
, p. 12481 - 12493 (2021/09/20)
An efficient methodology has been developed for the synthesis of tetra- and pentasubstituted pyrroles via oxidative self-dimerization of N-propargylamines catalyzed by silver benzoate in the presence of K2S2O8 in good yields. The protocol provides a simple route for the synthesis of both tetra- and pentasubstituted pyrroles with two carbonyl groups in the side chain. The methodology can be extended toward the synthesis of pyrrolo[3,4-d]pyridazine.
