132091-74-8

Basic information

• Product Name: 4-TERT-BUTYL-2-TRIFLUOROMETHYLCYCLOHEXANONE
• Synonyms: 4-TERT-BUTYL-2-TRIFLUOROMETHYLCYCLOHEXANONE
• CAS NO: 132091-74-8
• Molecular Formula: C₁₁H₁₇F₃O
• Molecular Weight: 222.25
• Mol File: 132091-74-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-TERT-BUTYL-2-TRIFLUOROMETHYLCYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TERT-BUTYL-2-TRIFLUOROMETHYLCYCLOHEXANONE(132091-74-8)
• EPA Substance Registry System: 4-TERT-BUTYL-2-TRIFLUOROMETHYLCYCLOHEXANONE(132091-74-8)

Safety Data

• Hazardous Substances Data: 132091-74-8(Hazardous Substances Data)

Upstream product

• 7360-39-6 1-acetoxy-4-tert-butylcyclohexene 
• 2926-29-6 Langlois reagent 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 77412-96-5 1-trifluoromethanesulfonyloxy-4-t-butylcyclohexene 
• 2314-97-8 iodotrifluoromethane 
• 66323-98-6 tert-butyl(4-tert-butylcyclohex-1-enyloxy)dimethylsilane 
• 19980-19-9 4-t-butyl-1-trimethylsilyloxy-1-cyclohexene 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 132091-64-6 C₁₆H₃₂GeO 

Relevant articles and documents

Radical trifluoromethylation of ketone Li enolates

It has generally been believed that highly basic Li enolates cannot be applied as substrates for radical trifluoromethylation due to defluorination of the α-CF3 product. However, Li enolates can be in fact employed for radical trifluoromethylat

Electrochemical Synthesis of Fluorinated Ketones from Enol Acetates and Sodium Perfluoroalkyl Sulfinates

The electrochemical synthesis of fluorinated ketones from enol acetates and RfSO2Na in an undivided cell under constant current conditions was developed. The electrosynthesis proceeded via perfluoroalkyl radical generation from sodium perfluoroalkyl sulfinate followed by addition to the enol acetate and transformation of the resulting C radical to a fluorinated ketone. The method is applicable to a wide range of enol acetates and results in the desired products in yields of 20 to 85%.

Erratum: Photoredox catalysis: A mild, operationally simple approach to the synthesis of α-trifluoromethyl carbonyl compounds (Angewandte Chemie - International Edition (2011) 50 (6119-6122))

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