132095-54-6

Basic information

• Product Name: 7-Bromo-2-tetralone
• Synonyms: 7-BROMO-3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE;7-BROMO-2-TETRALONE;2(1H)-Naphthalenone, 7-bromo-3,4-dihydro-;7-broMo-1,2,3,4-tetrahydronaphthalen-2-one;7-broMo-3,4-dihydronaphthalen-2-one
• CAS NO: 132095-54-6
• Molecular Formula: C₁₀H₉BrO
• Molecular Weight: 225.08
• Mol File: 132095-54-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 72-74 °C
• Boiling Point: 319.195 °C at 760 mmHg
• Flash Point: 108.661 °C
• Appearance: /
• Density: 1.511 g/cm³
• Vapor Pressure: 0.000344mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 7-Bromo-2-tetralone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Bromo-2-tetralone(132095-54-6)
• EPA Substance Registry System: 7-Bromo-2-tetralone(132095-54-6)

Safety Data

• Hazardous Substances Data: 132095-54-6(Hazardous Substances Data)

Usage

General Description

7-Bromo-2-tetralone, also known as BR-47456, is an organic compound represented by the molecular formula C10H7BrO. This chemical is classified under ketones and is a brominated derivative of tetralone. It is potentially useful for various applications in chemical research due to its functional group that makes it a suitable reactant in many organic synthesis reactions. Its characteristics include being a crystalline solid with a light yellow appearance. Proper handling is necessary as it may cause skin irritation, serious eye irritation, and may be harmful if inhaled or swallowed. Its physical and chemical properties can be accurately described with values such as a molecular weight of 227.06 g/mol and boiling point of 320.4°C at 760 mmHg. It must be stored in a cool, dry place, away from incompatible substances and heat sources.

InChI:InChI=1/C10H9BrO/c11-9-3-1-7-2-4-10(12)6-8(7)5-9/h1,3,5H,2,4,6H2

Upstream product

• 74-85-1 ethene 
• 1878-67-7 3-Bromophenylacetic acid 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 98288-51-8 2-(3-bromophenyl)acetyl chloride 

Relevant articles and documents

AMINO ALCOHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

The present invention belongs to the field of medicine, and specifically discloses an amino alcohol derivative represented by Formula I, a pharmaceutically acceptable salt, solvate, polymorph or prodrug thereof. In addition, the present invention also discloses a pharmaceutical composition comprising the above substances, and a use of the substance in the preparation of a medicament for the prevention and treatment of an immune inflammatory disease, or a disease or condition associated with immunological competence such as multiple sclerosis, ALS, CIDP, systemic lupus erythematosus, rheumatoid arthritis, ulcerative colitis, psoriasis, polymyositis, etc.

ANTIDIABETIC BICYCLIC COMPOUNDS

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF

The present invention provides a heterocyclic group contained amino-methanol derivative, and salt, a preparation method and use thereof, and belongs to the medical field. The heterocyclic group contained amino-methanol derivative and the salt thereof of the present invention are used for preparing medicines for immune suppression and for the treatment of organ transplant rejection , or medicines for treating immune mediated inflammatory diseases, such as multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis.