13212-58-3Relevant academic research and scientific papers
Synthesis and antimicrobial activity of some benzoxazinoids derivatives of 2-nitrophenol and 3-hydroxy-2-nitropyridine
Lima, William Gustavo,dos Santos, Flávio José,Cristina Soares, Adriana,Macías, Francisco A.,Molinillo, José M. G.,Maria Siqueira Ferreira, Jaqueline,Máximo de Siqueira, Jo?o
, p. 286 - 296 (2019)
Benzoxazinoids (BXs), alkaloids frequently found in Gramineae species, are natural defensives that can potentially be exploited to the development of novel antimicrobial agents. Here, BXs analogs were synthesized from 2-nitrophenol (benzoxazinone series)
Modified benzoxazinones in the system Oryza sativa-Echinochloa crus-galli: An approach To the development of biorational herbicide models
Macias, Francisco A.,Chinchilla, Nuria,Varela, Rosa M.,Molinillo, Jose M. G.,Marin, David,De Siqueira, Joao M.
experimental part, p. 9941 - 9948 (2010/07/05)
The utility of benzoxazinones and some of their synthetic derivatives in the search for new leads for herbicide model development has been explored. The work described focuses on obtaining derivatives that present selectivity in the system Oryza sativa-Echinochloa crus-galli. To achieve this goal the influence of lipophilicity in this system has been studied by preparing 14 ester derivatives at the N-4 position of D-DIBOA along with other compounds with different functionalization and chain lengths at position C-2. These compounds have been tested in the aforementioned system, and the dose-response profiles have been compared. The most active compound was 2-ethyl-4-hydroxy-(2H)-1,4- benzoxazin-3(4H)-one, which presented higher selectivity than the specific herbicide Cotanil-35. These results confirm the potential of D-DIBOA as a lead herbicide for the control of Echinochloa spp. in rice crops.
Synthesis and antimicrobial activity of some new 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones
Oezden, Seckin,Oeztuerk, Aydin Murat,Goeker, Hakan,Altanlar, Nurten
, p. 715 - 718 (2007/10/03)
Some 4-hydroxy-2H-1,4-benzoxazin-3(4H)-ones were synthesized and evaluated for their antimicrobial activities against Staphylococcus aureus, Escherichia coli and Candida albicans. Compounds 9, and 10 exhibited the best activity against Candida albicans. C
