132124-82-4

Usage

Uses

Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl-5-[(phenylimino)methyl]is used as a potential drug candidate for various therapeutic applications due to its unique structure and the presence of functional groups that can contribute to its reactivity and biological activity.
Used in Organic Synthesis:
2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl-5-[(phenylimino)methyl]is used as a building block in organic synthesis for the development of new compounds with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Used in Drug Development:
2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl-5-[(phenylimino)methyl]is used as a starting material or intermediate in the synthesis of new drugs, leveraging its unique structure and functional groups to create novel therapeutic agents with improved efficacy and selectivity.
Used in Agricultural Industry:
2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl-5-[(phenylimino)methyl]is used as a potential active ingredient in the development of new agrochemicals, such as pesticides or herbicides, due to its potential biological activity and reactivity with target organisms.

Upstream product

• 62-53-3 aniline 
• 181465-38-3 6-amino-1,3-dimethyl-5-thioformyluracil 
• 94839-46-0 5-[(dimethylamino)methylene]dihydro-6-imino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione monohydrochloride 
• 54660-80-9 6-amino-1,3-dimethyl-5-formyluracil 

Downstream Products

• 132124-95-9 5-Phenylaminomethyl-1,3-dimethyl-6-(triphenylphosphoranylidene)amino-uracil 
• 132124-98-2 7-(p-Chlorophenyl)amino-6-phenyl-1,3-dimethyl-1,2,3,4,5,6-hexahydropyrimido<4,5-d>pyrimidine 
• 132124-99-3 7-(p-Fluorophenyl)amino-6-phenyl-1,3-dimethyl-1,2,3,4,5,6-hexahydropyrimido<4,5-d>pyrimidine 
• 132198-81-3 7-(p-Methoxyphenyl)imino-6-phenyl-1,3-dimethyl-2,4-dioxo-1,2,3,4,6,7-hexahydropyrimido<4,5-d>pyrimidine 
• 132124-88-0 7-(p-Chlorophenyl)imino-6-phenyl-1,3-dimethyl-2,4-dioxo-1,2,3,4,6,7-hexahydropyrimido<4,5-d>pyrimidine 
• 132124-89-1 7-(p-Fluorophenyl)imino-6-phenyl-1,3-dimethyl-2,4-dioxo-1,2,3,4,6,7-hexahydropyrimido<4,5-d>pyrimidine 
• 132125-00-9 7-(p-Tolyl)amino-6-phenyl-1,3-dimethyl-1,2,3,4,5,6-hexahydropyrimido<4,5-d>pyrimidine 
• 132198-80-2 7-(p-Tolyl)imino-6-phenyl-1,3-dimethyl-2,4-dioxo-1,2,3,4,6,7-hexahydropyrimido<4,5-d>pyrimidine 
• 36226-16-1 5,7-dimethyl-2-phenyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione 
• 132124-85-7 5-<(N-Phenylimino)methyl>-1,3-dimethyl-6-<(triphenylphosphoranylidene)amino>uracil 

Relevant academic research and scientific papers

Reactivities of 6-amino-1,3-dimethyl-5-thioformyluracil toward nucleophiles and its application to synthesis of pyrido[2,3-d]pyrimidines

The reaction of the 5-thioformyluracil 1 with phenylhydrazine and various amines readily afforded the hydrazone 3a and Schiff bases 3b-d, respectively. Further, carbanions and Wittig reagents reacted with 1 to give pyrido[2,3-d]pyrimidines 4 and 9. The co

Iodobenzene diacetate-promoted N-N and N-O bond formation for pyrazolo- and isoxazolopyrimidine syntheses

Pyrazolo[3,4-d]pyrimidine-4,6-dione derivatives were efficiently synthesized via the intramolecular N-N bond coupling of 5-iminomethyl-6-aminouracil derivatives using iodobenzene diacetate. The oxidative coupling was also applied to the analogous N-O bond

Iminophosphorane-mediated synthesis of fused uracils. A facile one-pot preparation of pyrimido[4,5-d]pyrimidine derivatives

The aza Wittig-type reaction of iminophosphoranes 3, 5-[(N-Arylimino)methyl]-6- [(triphenylphosphoranylidene)amino]-1,3-dimethyl uracils, with aromatic isocyanates leads to the functionalized pyrimido[4,5-d]pyrimidines 4. Iminophosphoranes 5, prepared from 3 by selective reduction with sodium borohydride, undergo dihydropyrimido annelation by reaction with isocyanates to give 7-amino-6-aryl-1,3-dimethyl-1,2,3,4,5,6- hexahydropyrimido[4,5-d]pyrimidines 6.