132173-07-0

Basic information

• Product Name: SR 31747
• Synonyms: SR 31747;(Z)-N-[3-(3-CHLORO-4-CYCLOHEXYLPHENYL)PROP-2-ENYL]-N-ETHYLCYCLOHEXYLAMINE HYDROCHLORIDE;3-(3-Chloro-4-cyclohexylphenyl)-N-cyclohexyl-N-ethyl-2(Z)-propenylaMine;3-(3-Chloro-4-cyclohexylphenyl)-N-cyclohexyl-N-ethyl-2(Z)-propenylaMine hydrochloride;(Z)-N-(3-(3-Chloro-4-cyclohexylphenyl)allyl)-N-ethylcyclohexanamine;HKHPCMBPASXYGP-KVVVOXFISA-N
• CAS NO: 132173-07-0
• Molecular Formula: C23H35Cl2N
• Molecular Weight: 396.4367
• Mol File: 132173-07-0.mol

Chemical Properties

• Boiling Point: 479.9°C at 760 mmHg
• Flash Point: 244.1°C
• Appearance: /
• Vapor Pressure: 2.26E-09mmHg at 25°C
• CAS DataBase Reference: SR 31747(CAS DataBase Reference)
• NIST Chemistry Reference: SR 31747(132173-07-0)
• EPA Substance Registry System: SR 31747(132173-07-0)

Safety Data

• Hazardous Substances Data: 132173-07-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
SR 31747 is used as an antiarrhythmic agent for its ability to inhibit the reverse mode of the sodium-calcium exchanger, which helps in the treatment of cardiac arrhythmias.
Used in Neurological Applications:
SR 31747 is used as a neuroprotective agent for its potential to protect against conditions such as ischemic stroke and neurodegenerative diseases by maintaining intracellular calcium homeostasis and reducing neuronal damage.

InChI:InChI=1/C23H34ClN.ClH/c1-2-25(21-13-7-4-8-14-21)17-9-10-19-15-16-22(23(24)18-19)20-11-5-3-6-12-20;/h9-10,15-16,18,20-21H,2-8,11-14,17H2,1H3;1H/b10-9-;

Related news

The sigma ligand SR 31747 (cas 132173-07-0) prevents the development of acute graft-versus-host disease in mice by blocking IFN-γ and GM-CSF mRNA expression08/03/2019

SR 31747 is a sigma ligand which prevents the development of acute graft-versus-host reaction (GvHR) in hybrid B6D2F1 mice injected with C57BL/6 parental spleen cells. In the present study, we showed that this drug dramatically impaired the GvHR-associated increase in the numbers of both B-lymph...detailed

Relevant articles and documents

Benzene derivatives, their preparation and pharmaceutical compositions in which they are present

The present invention relates to compounds of the formula STR1 in which: p1 R1 is hydrogen or a halogen atom; R2 is a cyclohexyl or a phenyl; R3 is a (C3 -C6) cycloalkyl; R4 is hydrogen, (C