132194-21-9

Basic information

• Product Name: 6-Fluoro-2-amino-9-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-9H-purine
• Synonyms: (2S)-5α-(2-Amino-6-fluoro-9H-purine-9-yl)tetrahydrofuran-2α-methanol;2-Amino-6-fluoro-9-(2,3-dideoxy-β-D-ribofuranosyl)-9H-purine;6-Fluoro-2-amino-9-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-9H-purine
• CAS NO: 132194-21-9
• Molecular Formula: C₁₀H₁₂FN₅O₂
• Molecular Weight: 253.2329832
• Mol File: 132194-21-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 138-140 °C
• Boiling Point: 572.7°Cat760mmHg
• Flash Point: 300.1°C
• Appearance: /
• Density: 1.85g/cm³
• Vapor Pressure: 5.93E-14mmHg at 25°C
• Refractive Index: 1.795
• PKA: 14.44±0.10(Predicted)
• CAS DataBase Reference: 6-Fluoro-2-amino-9-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-9H-purine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Fluoro-2-amino-9-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-9H-purine(132194-21-9)
• EPA Substance Registry System: 6-Fluoro-2-amino-9-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-9H-purine(132194-21-9)

Safety Data

• Hazardous Substances Data: 132194-21-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12FN5O2/c11-8-7-9(15-10(12)14-8)16(4-13-7)6-2-1-5(3-17)18-6/h4-6,17H,1-3H2,(H2,12,14,15)/t5-,6+/m0/s1

Upstream product

• 34798-94-2 2-amino-6-fluoropurine 
• 5983-09-5 2',3'-Dideoxyuridine 
• 122970-35-8 2-amino-6-chloro-9-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-9H-purine 

Relevant articles and documents

Nucleic acid related compounds. 114. Synthesis of 2,6-(disubstituted)purine 2′,3′-dideoxynucleosides and selected cytotoxic, anti-hepatitis B, and adenosine deaminase substrate activities

Selected 2,6-(disubstituted)purine 2′,3′-didehydro-2′,3′-dideoxynucleosides and 2′,3′-dideoxynucleosides were prepared and evaluated. Treatment of 5′-protected ribonucleosides with phenoxythiocarbonyl chloride and 4-(dimethylamino)pyridine, or under Schot