132198-53-9

Basic information

• Product Name: 2-phenyl[1,3]oxazolo[4,5-c]quinolin-4(5H)-one
• Synonyms: 2-Phenyl[1,3]oxazolo[4,5-c]quinolin-4-ol; 2-Phenyl-oxazolo(4,5-c)quinolin-4-one
• CAS NO: 132198-53-9
• Molecular Formula: C₁₆H₁₀N₂O₂
• Molecular Weight: 262.2628
• Mol File: 132198-53-9.mol
• Article Data: 5

Chemical Properties

• Density: 1.311g/cm³
• Refractive Index: 1.642
• CAS DataBase Reference: 2-phenyl[1,3]oxazolo[4,5-c]quinolin-4(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl[1,3]oxazolo[4,5-c]quinolin-4(5H)-one(132198-53-9)
• EPA Substance Registry System: 2-phenyl[1,3]oxazolo[4,5-c]quinolin-4(5H)-one(132198-53-9)

Safety Data

• Hazardous Substances Data: 132198-53-9(Hazardous Substances Data)

Upstream product

• 587884-70-6 ethyl 2-phenyl-5-(2-nitrophenyl)oxazole-4-carboxylate 
• 39819-39-1 2-phenyl-oxazole-4-carboxylic acid ethyl ester 
• 23012-16-0 2-phenyl-1,3-oxazole-4-carboxylic acid 
• 587884-71-7 ethyl 5-(2-aminophenyl)-2-phenyloxazole-4-carboxylate 
• 587884-72-8 2-phenyl-oxazole-4-carboxylic acid (2-iodo-phenyl)-amide 
• 5570-18-3 2-aminophenylboronic acid 
• 460081-28-1 5-bromo-2-phenyl-oxazole-4-carboxylic acid ethyl ester 
• 184536-36-5 3-benzoilaminoquinoline 

Downstream Products

• 129377-61-3 5-methyl-2-phenyl-oxazolo<4,5-c>quinolin-4(5H)-one 

Relevant articles and documents

4-Hydroxy-2-quinolones. 36. Synthesis of 2-R-oxazolo[4,5-c]quinolin-4(5H)-ones

We consider different variants for synthesis of 2-R-oxazolo[4,5-c]quinolin-4(5H)-ones based on 3-amino-1H-2-oxo-4-hydroxyquinolines and their 3-N-acyl derivatives. We show that in the latter case, formation of the oxazole ring is possible via two routes,

NOVEL QUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES SUCH AS ASTHMA OR ATOPIC DERMATITIS INCLUDING THE QUINOLINONE DERIVATIVE AS ACTIVE INGREDIENT

The present invention relates to anovel quinolinone derivative compound that regulates intracellular signal transduction mediated by TSLP and IL-33 to exhibit efficacy in preventing or treating allergic diseases such as asthma or atopic dermatitis. The qu

Certain oxazoloquinolinones; a new class of GABA brain receptor ligands

This invention encompasses compounds of the formula: STR1 and the pharmaceutically acceptable non-toxic salts thereof wherein R 1, R 2, R 3, R 4, and W are variablesThese compounds are highly selective agonists, antagonists or inverse agonists for GABA a