1322052-38-9Relevant academic research and scientific papers
Tartaric acid-catalyzed synthesis of α-aminophosphonates under solvent-free conditions
Gangwar, Nidhi,Kasana, Virendra Kumar
, p. 2800 - 2804 (2011)
A facile procedure is developed for the synthesis of α- aminophosphonates, using tartaric acid as a stable, environmentally benign, low cost, and easily available organocatalyst. In the presence of tartaric acid (10 mol%), triethyl phosphite reacts with imines (generated in situ from an aldehyde and an amine) to yield the corresponding α-aminophosphonates. The organocatalyst tartaric acid is more stable during reaction. The catalyst provides easier workup, affords better yields, and takes less reaction time in comparison to generally used Lewis acid catalysts. Taylor & Francis Group, LLC.
