1322062-57-6

Basic information

• Product Name: Moxifloxacin Decarboxy Analog
• Synonyms: Moxifloxacin Decarboxy Analog;Decarboxy Moxifloxacin 1;1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxyquinolin-4(1H)-one;Moxifloxacin impurity X;1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-methoxyquinolin-4(1H)-one hydrochloride
• CAS NO: 1322062-57-6
• Molecular Formula: C20H24FN3O2
• Molecular Weight: 357.42
• Mol File: 1322062-57-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 561.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.300±0.06 g/cm3(Predicted)
• PKA: 10.63±0.20(Predicted)
• CAS DataBase Reference: Moxifloxacin Decarboxy Analog(CAS DataBase Reference)
• NIST Chemistry Reference: Moxifloxacin Decarboxy Analog(1322062-57-6)
• EPA Substance Registry System: Moxifloxacin Decarboxy Analog(1322062-57-6)

Safety Data

• Hazardous Substances Data: 1322062-57-6(Hazardous Substances Data)

Usage

Uses

A degradation product of Moxifloxacin (M745000). Moxifloxacin impurity.

Upstream product

• 151096-09-2 moxifloxacin 

Relevant articles and documents

Synthesis and evaluation of 1-cyclopropyl-2-thioalkyl-8-methoxy fluoroquinolones

Novel fluoroquinolone derivatives substituted with a 2-thioalkyl moiety, with and without a concomitant 3-carboxylate group, were synthesized to evaluate the effect of C-2 thioalkyl substituents on gyrase binding and inhibition. The presence of a 2-thioalkyl group universally decreased activity as compared to parent fluoroquinolones. However, with derivatives of moxifloxacin the presence of either a 2-thioalkyl group or a 3-carboxylate moiety increased activity over the 2,3-unsubstituted derivative. Energy minimization of structures provides an explanation for relative activities of fluoroquinolones having a C-2 thio moiety.