Welcome to LookChem.com Sign In|Join Free
  • or
Propanamide, 2-amino-3-methoxy-N-(phenylmethyl)-, hydrochloride (1:1), (2R)-, also known as Levomethadone hydrochloride, is a chemical compound that functions as an opioid analgesic and medication for opioid use disorder. It is a hydrochloride salt, which allows for oral or injectable administration, and is utilized to manage moderate to severe pain conditions. Levomethadone operates by binding to the opioid receptors in the brain and spinal cord, thereby diminishing the sensation of pain and inducing a tranquilizing effect. Due to its high potential for abuse and addiction, it is classified as a Schedule II controlled substance and is strictly regulated and prescribed by healthcare professionals.

1322062-76-9

Post Buying Request

1322062-76-9 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1322062-76-9 Usage

Uses

Used in Pharmaceutical Industry:
Levomethadone hydrochloride is used as an analgesic for the management of moderate to severe pain. It is effective due to its action on opioid receptors, which helps in reducing the perception of pain and providing a calming effect to the patient.
Used in Opioid Use Disorder Treatment:
In addition to its analgesic properties, Levomethadone hydrochloride is also utilized as a medication for treating opioid use disorder. It aids in managing withdrawal symptoms and cravings associated with opioid dependence, thereby supporting the recovery process under the supervision of healthcare professionals.

Check Digit Verification of cas no

The CAS Registry Mumber 1322062-76-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,2,2,0,6 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1322062-76:
(9*1)+(8*3)+(7*2)+(6*2)+(5*0)+(4*6)+(3*2)+(2*7)+(1*6)=109
109 % 10 = 9
So 1322062-76-9 is a valid CAS Registry Number.

1322062-76-9Relevant academic research and scientific papers

Improved Synthesis and Impurity Identification of (R)-Lacosamide

Yang, Anjiang,Hu, Feifei,Li, Zhong,Chen, Mengdi,Cai, Jianguang,Wang, Linghui,Zhang, Tao,Zhao, Chuanmeng,Zhang, Fuli

, p. 818 - 824 (2019/04/01)

An improved synthesis of Lacosamide 1 with high purity has been developed. Critical parameters of each step were identified as well as the impurities generated. Moreover, a creative method to improve chiral purity and stability of the key intermediate (R)-2-amino-N-benzyl-3-methoxypropionamide 10 by forming salt with an achiral acid (phosphoric acid) was discovered to ensure the chiral purity of (R)-Lacosamide. Phosphoric acid was further developed for the deprotection of the Boc group.

AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE

-

, (2018/04/17)

The present invention relates to an improved process for the synthesis of (R)- Lacosamide in which free base of O-methyl-N-benzyl-D-Serinamide is not isolated before acylation. The process avoids the use of column chromatography and chiral resolution for the preparation of different stages of Lacosamide.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 1322062-76-9