1322081-35-5

Basic information

• Product Name: [3,5-dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-acetic acid methyl ester
• Synonyms: [3,5-dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-acetic acid methyl ester
• CAS NO: 1322081-35-5
• Molecular Weight: 303.318
• Mol File: 1322081-35-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: [3,5-dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [3,5-dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-acetic acid methyl ester(1322081-35-5)
• EPA Substance Registry System: [3,5-dimethyl-1-(4-nitro-benzyl)-1H-pyrazol-4-yl]-acetic acid methyl ester(1322081-35-5)

Safety Data

• Hazardous Substances Data: 1322081-35-5(Hazardous Substances Data)

Upstream product

• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 56699-23-1 (3,5-dimethyl-1H-pyrazol-4-yl)acetic acid methyl ester 
• 32701-82-9 (1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)acetic acid 
• 1283378-96-0 (1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)-acetic acid methyl ester 

Downstream Products

• 1322081-38-8 [1-(4-aminobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid methyl ester 
• 1322082-81-4 [1-(4-benzyloxycarbonylamino-benzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-acetic acid 
• 1322083-00-0 {1-[4-(3-benzyl-ureido)-benzyl]-3,5-dimethyl-1H-pyrazol-4-yl}-acetic acid 
• 1322083-01-1 [1-(4-benzenesulfonylamino-benzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-acetic acid 
• 1322083-08-8 {1-[4-(4-chloro-benzylamino)-benzyl]-3,5-dimethyl-1H-pyrazol-4-yl}-acetic acid 
• 1322084-19-4 N-{4-[(3,5-dimethyl-4-{[(2-methylpropane-2-sulfonyl)carbamoyl]methyl}-1H-pyrazol-1-yl)methyl]phenyl}-4-(trifluoromethyl)benzamide 
• 1322081-31-1 {3,5-dimethyl-1-[4-(4-trifluoromethyl-benzoylamino)-benzyl]-1H-pyrazol-4-yl}-acetic acid 
• 1391466-21-9 (1-{4-[(5-fluoro-3-methylbenzofuran-2-carbonyl)amino]benzyl}-3,5-dimethyl-1H-pyrazol-4-yl)acetic acid 
• 1391467-59-6 (1-{4-[(5-fluoro-3-methylbenzofuran-2-carbonyl)amino]benzyl}-3,5-dimethyl-1H-pyrazol-4-yl)acetic acid methyl ester 

Relevant articles and documents

Pyrazole Compounds as CRTH2 Antagonists

Pyrazole compounds of formula (Ia) or (Ib) and pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Y1, Y2, Y3, Y4, Y5, Z, R1, Rsu

PYRAZOLE COMPOUNDS AS CRTH2 ANTAGONISTS

The present invention relates to pyrazole compounds of formula (1a) or (1b) and pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Y1, y2, y3, y4, y5, Z, R1, R2, n and R3 have one of the meanings as indicated in the specification and claims, to their use as medicaments, to pharmaceutical formulation containing said compounds and to pharmaceutical formulations said compounds in combination with one or more active substances. The compounds have CRTH2 antagonistic activity.