1322084-98-9Relevant academic research and scientific papers
Enantioconvergent Amination of Racemic Tertiary C-H Bonds
Lang, Kai,Li, Chaoqun,Kim, Isaac,Zhang, X. Peter
supporting information, p. 20902 - 20911 (2020/12/22)
Racemization is considered to be an intrinsic stereochemical feature of free radical chemistry as can be seen in traditional radical halogenation reactions of optically active tertiary C-H bonds. If the facile process of radical racemization could be effe
Isomerization of olefins triggered by rhodium-catalyzed C-H bond activation: Control of endocyclic β-hydrogen elimination
Yip, Stephanie Y. Y.,A?ssa, Christophe
supporting information, p. 6870 - 6873 (2015/06/02)
Five-membered metallacycles are typically reluctant to undergo endocyclic β-hydrogen elimination. The rhodium-catalyzed isomerization of 4-pentenals into 3-pentenals occurs through this elementary step and cleavage of two C-H bonds, as supported by deuterium-labeling studies. The reaction proceeds without decarbonylation, leads to trans olefins exclusively, and tolerates other olefins normally prone to isomerization. Endocyclic β-hydrogen elimination can also be controlled in an enantiodivergent reaction on a racemic mixture.
Palladium-catalyzed haloallylation of aromatic ynol ethers with allyl chlorides: A highly regio- and stereoselective approach to (1E)-α- chloroenol ethers
Cai, Haiting,Yuan, Zheliang,Zhu, Weidong,Zhu, Gangguo
scheme or table, p. 8682 - 8684 (2011/09/15)
Described herein is a Pd-catalyzed haloallylation of aromatic ynol ethers and allyl chlorides, allowing facile access to (1E)-α-chloroenol ethers in a highly regio- and stereoselective manner. The synthetic utility of this method is demonstrated well by t
