132269-81-9Relevant academic research and scientific papers
A Novel Synthesis of the Isoxazoloacridine Ring System
Shutske, Gregory M.
, p. 1617 - 1621 (2007/10/02)
The Schmidt reaction of 6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5H)-one (1) is described.In addition to the expected isomeric lactams, 3-phenyl-5,6,7,8-tetrahydro-4H-isoxazoloazepin-4-one (3) and 7,8-dihydro-3-phenyl-4H-isoxazoloazepin-5(6H)-one (4), 4-amino-3-phenyl-1,2-benzisoxazole (5) was isolated, along with 4,5-dihydro-3H-isoxazoloacridine (6).Possible mechanisms for the formation of these products are discussed and some chemistry of the little-known ring system represented by 6 is also described.
