1322697-83-5Relevant academic research and scientific papers
Ruthenium-catalyzed annulation of alkynes with amides via formyl translocation
Wu, Cui-Yan,Hu, Ming,Liu, Yu,Song, Ren-Jie,Lei, Yong,Tang, Bo-Xiao,Li, Rong-Jiang,Li, Jin-Heng
supporting information; experimental part, p. 3197 - 3199 (2012/05/07)
The first example of Ru-catalyzed intramolecular annulation of alkynes with amides via formyl translocation has been developed, which provides an efficient approach for the synthesis of 1H-indole-3-carbaldehydes. The Royal Society of Chemistry 2012.
Direct transformation of N, N -dimethylformamide to -CN: Pd-catalyzed cyanation of heteroarenes via C-H functionalization
Ding, Shengtao,Jiao, Ning
supporting information; experimental part, p. 12374 - 12377 (2011/10/02)
This paper describes the direct cyanation of indoles and benzofurans employing N,N-dimethylformamide (DMF) as both reagent and solvent. Isotopic labeling experiments indicated that both the N and the C of the cyano group derived from DMF. This transformation offers an alternative method for preparing aryl nitriles, though it is currently limited in scope to indoles and benzofurans.
