1322751-68-7Relevant academic research and scientific papers
Exo-selective asymmetric inverse-electron demand hetero-diels-alder reaction catalyzed by Cu(II)-hydroxy oxazoline ligands
Barba, Andrea,Barroso, Santiago,Blay, Gonzalo,Cardona, Luz,Melegari, Martina,Pedro, José R.
experimental part, p. 1592 - 1596 (2011/08/03)
Cu(II) complexes of hydroxy oxazolines derived from (+)-(S)-ketopinic acid catalyze the asymmetric hetero-Diels-Alder cycloaddition of enol ethers and ,-unsaturated -keto esters. The reaction takes place with unprecedented exo selectivity providing 2,4-trans-disubstituted chiral 2,3-dihydropyrans with up to 88% ee. Georg Thieme Verlag Stuttgart ? New York.
