13228-05-2

Upstream product

• 33854-16-9 (+)-prostaglandin F_2α 
• 78478-37-2 methyl (6R,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxy-5-(phenylseleno)-prosta-13-en-1-oate 
• 78478-38-3 methyl (6S,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxy-5-(phenylseleno)-prosta-13-en-1-oate 
• 88365-23-5 Biphenyl-4-carboxylic acid 2-[(1R,2R,3R,5R)-3,5-bis-benzyloxy-2-((E)-3-hydroxy-oct-1-enyl)-cyclopentyl]-ethyl ester 
• 88391-38-2 (15R)-9,11-Dibenzyl-PGF_2β 
• 88365-26-8 {(1R,2R,3R,5R)-3,5-Bis-benzyloxy-2-[(E)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-acetaldehyde 
• 88365-25-7 2-{(1R,2R,3R,5R)-3,5-Bis-benzyloxy-2-[(E)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-ethanol 
• 88365-24-6 Biphenyl-4-carboxylic acid 2-{(1R,2R,3R,5R)-3,5-bis-benzyloxy-2-[(E)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-ethyl ester 
• 186581-53-3 diazomethane 
• 38310-95-1 (15R)-PGF_2β 
• 55022-57-6 (Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-3-hydroxy-2-((E)-3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid methyl ester 
• 88365-27-9 (Z)-7-{(1R,2R,3R,5R)-3,5-Bis-benzyloxy-2-[(E)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-hept-5-enoic acid 

Downstream Products

• 33854-16-9 (+)-prostaglandin F_2α 

Relevant academic research and scientific papers

Prostaglandins. 2. Synthesis of Prostaglandin F2α in Optically Active Form from Chiral Precursors

A synthetic route to optically active prostaglandins is described which use chiral starting materials.Acylation of the bis(magnesiobromide) salt of methyl hemimalonate with (S)-(-)-2-acetoxysuccinyl chloride led to unstable dimethyl (S)-4-acetoxy-3,6-diox

Organoselenium-based synthesis of oxygen-containing prostacyclins

The application of organoselenium-induced ring closures to the synthesis of stable, oxygen-containing prostacyclins is described. The strategy involves utilization of PGF2α methyl ester (3) as a starting material in a PhSeCl-induced cyclization

8β,12α,15β-PGF2 β Compounds

This invention is a group of 8-beta, 12-alpha-PG2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.