13229-95-3

Usage

Main use

Production of UV-curable coatings, adhesives, and inks

Ability

Undergoes photopolymerization and forms a crosslinked network when exposed to ultraviolet light

Safety concerns

Considered a skin and eye irritant, may cause respiratory irritation if inhaled

Handling

Important to handle with caution and adhere to proper safety and handling procedures

Upstream product

• 905406-44-2 C₁₇H₁₇NO₃ 
• 105-56-6 ethyl 2-cyanoacetate 
• 121-32-4 4-hydroxy-3-ethoxybenzaldehyde 

Relevant academic research and scientific papers

Synthesis and characterization of ionic liquid based bifunctional periodic mesoporous organosilica supported potassium carbonate as very efficient nanocatalyst for the Knoevenagel condensation

A novel ionic liquid based bifunctional periodic mesoporous organosilica supported potassium carbonate (BPMO-IL-KCO3) is prepared, characterized and its catalytic efficiency is studied in the Knoevenagel reaction. The BPMO-IL-KCO3 wa

Simple, efficient, and green method for synthesis of trisubstituted electrophilic alkenes using lipase as a biocatalyst

A simple and efficient Knoevenagel condensation method for the synthesis of trisubstituted electrophilic alkenes was developed using lipase as a biocatalyst. Knoevenagel condensation was performed using the conventional method and using lipases (Aspergillus oryzae or Rhizopus oryzae) as biocatalysts, and reaction time, reaction temperature, yield, and recyclability were compared. Using a lipase as a biocatalyst eliminated the need for bases such as piperidine and pyridine. A wide range of aromatic aldehydes and ketones readily undergo condensation with active methylene compounds. The workup procedure is also very simple, and yields of the reactions are in the range of 75%to 95%. Both the biocatalysts were effectively recycled four times with no major decrease in the yield of product. The remarkable catalytic activity and reusability of lipase widens its applicability in Knoevenagel condensation with good to excellent yields for synthesis of trisubstituted electrophilic alkenes.Copyright Taylor & Francis Group, LLC.

Reaction of ethyl cyanoacetate with benzal-4-acetylanilines: An unexpected result

Reaction of ethyl cyanoacetate with benzal-4-acetylanilines 1a-10a, the compounds containing both azomethine and ketone linkages, in equimolar ratio, in the presence of pyridine yields solid products, which have been characterized as ethyl benzal-cyanoacetate and its derivatives 1b-10b on the basis of elemental analysis and spectral studies. The reaction of 1a-10a with two moles of ethyl cyanoacetate also results in the formation of the same products 1b-10b, by an unexpected attack of ethyl cyanoacetate on azomethine linkage only rather than on both the reactive centres i.e. carbon-nitrogen double bond and carbon-oxygen double bond.