132294-63-4

Upstream product

• 82305-37-1 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranosyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 149113-51-9 2,3,2',3'-tetra-O-benzyl-4,6;4',6'-di-O-benzylidene-α,α-D-trehalose 

Downstream Products

• 73892-58-7 4,6-diacetamido-2,3-di-O-benzyl-4,6-dideoxy-α-D-glucopyranosyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 73892-57-6 4,6-diamino-2,3-di-O-benzyl-4,6-dideoxy-α-D-glucopyranosyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 73892-61-2 2,3-di-O-benzyl-4,6-dichloro-4,6-dideoxy-α-D-galactopyranosyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 132183-33-6 2,3,6-tri-O-benzyl-α-D-glucopyranosyl 2,3,6-tri-O-benzylidene-α-D-glucopyranoside 

Relevant academic research and scientific papers

Desymmetrization of trehalose via regioselective DIBAL reductive ring opening of benzylidene and substituted benzylidene acetals

Trehalose dibenzylidene and substituted dibenzylidene acetals were reductively opened either at O6 or O4 in a regioselective manner by using a DIBAL stock solution prepared in toluene or dichloromethane, respectively, to achieve desymmetrization of the trehalose core. The method was applied to synthesize various biologically important unsymmetrically substituted trehalose glycoconjugates, including a mycobacterial trisaccharide, a 4-epi-trehalosamine analog and a maradolipid.

α-D-Glycosyl-Substituted α,α-D-Trehaloses with (1 -> 4)-Linkage: Syntheses and NMR Investigations

Two symmetrical trehalose glycosyl 'acceptors' 4 and 6 were prepared and three of the unsymmetrical type, 8, 10, and 11.Glucosylation of symmetrical 'acceptor'4 gave a higher yield of trisaccharide (44percent) than protective-group manipulation, namely vi