1323119-01-2Relevant academic research and scientific papers
Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: Compounds with moderate to low opioid-receptor affinity
Li, Feng,Folk, John E.,Cheng, Kejun,Kurimura, Muneaki,Deck, Jason A.,Deschamps, Jeffrey R.,Rothman, Richard B.,Dersch, Christina M.,Jacobson, Arthur E.,Rice, Kenner C.
experimental part, p. 4330 - 4337 (2011/08/10)
N-Phenethyl-substituted ortho-a and para-a oxide-bridged phenylmorphans have been obtained through an improved synthesis and their binding affinity examined at the various opioid receptors. Although the N-phenethyl substituent showed much greater affinity
