1323140-65-3

Basic information

• Product Name: C₂₁H₂₀ClN₃O₄
• CAS NO: 1323140-65-3
• Molecular Weight: 413.861
• Mol File: 1323140-65-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₀ClN₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₀ClN₃O₄(1323140-65-3)
• EPA Substance Registry System: C₂₁H₂₀ClN₃O₄(1323140-65-3)

Safety Data

• Hazardous Substances Data: 1323140-65-3(Hazardous Substances Data)

Upstream product

• 297146-14-6 C₂₁H₂₁N₃O₄ 
• 110-89-4 piperidine 
• 15601-50-0 2-(p-Nitrophenyl)-4-benzylidene-2-oxazolin-5-one 

Relevant articles and documents

Synthesis and Quantitative Structure-activity Relationships Study for Arylpropenamide Derivatives as Inhibitors of Hepatitis B Virus Replication

A series of new arylpropenamide derivatives containing different aryl groups were synthesized, characterized, and evaluated for their anti-hepatitis B virus (HBV) activities. A new high accuracy QSAR model of arylpropenamide was constructed based on a more completely activities data and calculation parameter. The 2D-QSAR equations, by using DFT and multiple linear regression analysis methods, revealed that higher value of thermal energy (TE) and lower entropy (S?) increase the anti-HBV activities of the arylpropenamide molecules. Predictive 3D-QSAR models were established by SYBYL multifit molecular alignment rule. The optimum models were all statistically significant with cross-validated and conventional coefficients, indicating that they were reliable enough for activity prediction.