1323153-37-2

Upstream product

• 90-47-1 xanth-9-one 
• 5396-28-1 4-methylxanthen-9-one 
• 20735-05-1 9,9-Dichloroxanthene 
• 334541-93-4 9,9-Dimethoxyxanthene 

Downstream Products

• 1316277-32-3 3-[2'-hydroxy-3'-methylphenyl]-1,2-benzisoxazole 2-oxide 
• 1316277-37-8 C₁₄H₁₁NO₃ 
• 1323153-50-9 C₂₁H₁₈N₂O₃ 

Relevant academic research and scientific papers

Xanthones in heterocyclic synthesis. An efficient route for the synthesis of C-3 o-Hydroxyaryl substituted 1, 2-benzisoxazoles and their N-oxides, potential scaffolds for angiotensin(II) antagonist hybrid peptides

Regioselective substitution of xanthone and its nucleophilic cleavage allow the synthesis of C-3 ohydroxyaryl substituted 1, 2-benzisoxazoles or their V-oxides by cyclodehydration or oxidative cyclization of their corresponding ketoxime precursors, respectively. Molecular modeling analysis and 1H NMR spectra indicate an intramolecular H-bonding engaging phenol OH and the isoxazole ring N atom. The Japan Institute of Heterocyclic Chemistry.

Xanthones in heterocyclic synthesis. An efficient and general route for the synthesis of regioselectively substituted phthalazines

Xanthone undergoes regioselective substitution and nucleophically - triggered ring opening to the corresponding ketone. Hydrazone of the latter oxidatively rearranges to ortho-diacylarenes, which, then, with hydrazine gives regioselectively substituted phthalazines. Molecular modeling analysis and 1HNMR spectra indicate an intramolecular H-bonding engaging phenol OH and phthalazine N-3 atom.