132324-32-4

Basic information

• Product Name: N-[1-(3,4-dimethoxyphenyl)ethyl]-3,3-diphenylpropan-1-amine
• Synonyms: KHL 8430
• CAS NO: 132324-32-4
• Molecular Formula: C₂₅H₂₉NO₂
• Molecular Weight: 375.5033
• Mol File: 132324-32-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 509.6°C at 760 mmHg
• Flash Point: 222.7°C
• Density: 1.061g/cm³
• Vapor Pressure: 1.68E-10mmHg at 25°C
• Refractive Index: 1.566
• PKA: pKa 10.60 ± 0.05(H2O,t =25.0±0.1,I=0.1(NaCl)) (Uncertain)
• CAS DataBase Reference: N-[1-(3,4-dimethoxyphenyl)ethyl]-3,3-diphenylpropan-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-(3,4-dimethoxyphenyl)ethyl]-3,3-diphenylpropan-1-amine(132324-32-4)
• EPA Substance Registry System: N-[1-(3,4-dimethoxyphenyl)ethyl]-3,3-diphenylpropan-1-amine(132324-32-4)

Safety Data

• Hazardous Substances Data: 132324-32-4(Hazardous Substances Data)

Upstream product

• 5586-73-2 3-diphenylpropyl amine 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 

Relevant articles and documents

Synthesis and biological activity of allosteric modulators of GABA B receptors, Part 1. N-(Phenylpropyl)-1-arylethylamines

A series of 15 analogues of fendiline, and 34 derivatives of N-(3-phenylpropyl)-1-arylethylamine have been prepared for evaluation as positive allosteric modulators of GABAB receptors. The most active (EC50, 10 nM) was N-(3,3-diphenylpropyl)-1-(3-chloro-4-methoxyphenyl) ethylamine 6g. CSIRO 2006.