132331-48-7Relevant academic research and scientific papers
Stereocontrol in the Mukaiyama Aldol Addition to Chiral α- and β-Thio-Substituted Aldehydes
Annunziata, Rita,Cinquini, Mauro,Cozzi, Franco,Cozzi, Pier Giorgio,Consolandi, Emanuela
, p. 456 - 461 (2007/10/02)
A series of racemic α-thio-, β-thio-, and α-methyl-β-thio-substituted aldehydes has been prepared, and their Lewis acid promoted aldol condensation with nonstereogenic and stereogenic silylketene acetals and silyl enolethers has been studied.With α-thio-s
Diastereoselective Addition of a Silylketene Acetal to Chiral α-Thioaldehydes
Annunziata, Rita,Cinquini, Mauro,Cozzi, Franco,Cozzi, Pier Giorgio
, p. 6733 - 6736 (2007/10/02)
Chiral α-thioaldehydes 2-6 undergo chelation or non-chelation controlled addition of silylketene acetal 1, depending on the nature of the Lewis acid catalyst and of the ligands at the stereocenter.
