1323310-58-2

Upstream product

• 1323310-68-4 N-(3-methyl-1-(phenylsulfonyl)butyl)-p-toluenesulfonamide 
• 123-38-6 propionaldehyde 
• 590-86-3 isovaleraldehyde 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 1323310-74-2 N-((2R,3R)-2,5-dimethyl-1-hydroxyhexan-3-yl)-p-toluenesulfonamide 

Relevant academic research and scientific papers

PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-AMINO ALDEHYDE COMPOUND

The invention relates to a method of producing optically active β-aminoaldehyde compound (3) by reacting imine compound (1-1) or sulfone compound (1-2) with aldehyde compound (2) in the presence of an optically active pyrrolidine compound. wherein each sy

Asymmetric Mannich reaction of imines derived from aliphatic and aromatic aldehydes catalyzed by diarylprolinol silyl ether

Anti Mannich, try this! A direct asymmetric Mannich reaction catalyzed by a diarylprolinol silyl ether was developed to afford the anti-Mannich product with excellent enantioselectivity. Imines derived from both aliphatic and aromatic aldehydes were successfully used to obtain the synthetically important β-amino aldehydes (see scheme; Ts=tosyl). The reaction can also be performed in the presence of water. Copyright