1323389-49-6

Basic information

• Product Name: C₁₉H₁₅F₃O₃
• Synonyms: C₁₉H₁₅F₃O₃
• CAS NO: 1323389-49-6
• Molecular Weight: 348.322
• Mol File: 1323389-49-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₅F₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₅F₃O₃(1323389-49-6)
• EPA Substance Registry System: C₁₉H₁₅F₃O₃(1323389-49-6)

Safety Data

• Hazardous Substances Data: 1323389-49-6(Hazardous Substances Data)

Upstream product

• 198345-82-3 (4-(trifluoromethyl)phenyl)zinc(II) bromide 

Relevant articles and documents

Synthesis, crystal structure, characterization and antifungal activity of 3,4-diaryl-1H-Pyrazoles derivatives

A series of 3,4-diaryl-1H-pyrazoles derivatives were designed and synthesized by the reaction of 3-heteroarylchromones and 3-phenylchromones with hydrazine hydrate in good yields. All of those compounds were characterized by 1H NMR, 13C NMR, IR, and HRMS. Moreover, 3-(2,4-dihydroxyphenyl)-4-(4-hydroxyphenyl)-1H-pyrazole and 3-(2,4-dihydroxy phenyl)-4-(4-methoxyphenyl)-1H-pyrazole were further conformed by the single crystal X-ray diffraction. In addition, the antifungal activity against five phytopathogenic fungi (Cytospora sp., Colletotrichum gloeosporioides, Botrytis cinerea, Alternaria solani and Fusarium solani) of 3,4-diaryl-1H-pyrazoles were evaluated. 3-(2-Hydroxy-4-isopropoxyphenyl)-4-phenyl-1H-pyrazole was more better and broader inhibitory effect on Cytospora sp., C. gloeosporioides, A. solani and Fusarium solani with IC50 values of 26.96, 28.84, 16.77 and 22.10 μg/mL, respectively. 4-(4-Fluorophenyl)-3-(2-hydroxy-4-methoxyphenyl)-1H-pyrazole exhibited fairly effective antifungal activity against Cytospora sp., C. gloeosporioides and A. solani with IC50 values of 11.91, 14.92 and 16.98 μg/mL, respectively.