1323394-04-2Relevant articles and documents
Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy) propyl]nucleoside alkoxyalkyl esters: Inhibitors of hepatitis C virus and HIV-1 replication
Valiaeva, Nadejda,Wyles, David L.,Schooley, Robert T.,Hwu, Julia B.,Beadle, James R.,Prichard, Mark N.,Hostetler, Karl Y.
, p. 4616 - 4625 (2011/09/19)
We reported previously that octadecyloxyethyl 9-(S)-[3-hydroxy-2- (phosphonomethoxy)-propyl]adenine (ODE-(S)-HPMPA) was active against genotype 1b and 2a hepatitis C virus (HCV) replicons. This is surprising because acyclic nucleoside phosphonates have be