132354-25-7Relevant articles and documents
2-Dialkylamino-thiazolin-4-ones from α-Thiocyanato-carboxylic Acid Derivatives
Zimmermann, T.,Fischer, G. W.,Olk, B.
, p. 540 - 546 (2007/10/02)
α-Thiocyanato-acetic acid esters 1 a-c or amide 1 d react with dialkylamine salts of weak acids to give 2-dialkylamino-thiazolin-4-ones 2 a-f.The reaction can be performed using aliphatic alcohols, dipolar aprotic solvents or halogenated hydrocarbons as reaction medium or by heating the educts at 90 deg C without any solvent.According to the latter method, the 5-substituted thiazolinones 2 g, h are obtained from α-thiocyanatopropionic acid ethyl ester (1 d) or α-thiocyanato-phenylacetic acid ethyl ester (1 e) and dimethylamine actetate. - I.r., u.v. and n.m.r. data of the thiazolinones 2 are reported.