132372-78-2

Basic information

• Product Name: 1H-Tetrazole,5-[(4-ethoxyphenyl)methyl]-(9CI)
• Synonyms: 1H-Tetrazole,5-[(4-ethoxyphenyl)methyl]-(9CI)
• CAS NO: 132372-78-2
• Molecular Formula: C₁₀H₁₂N₄O
• Molecular Weight: 204.22848
• Product Categories: ETHOXY
• Mol File: 132372-78-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 138 °C
• Boiling Point: 402.1±47.0 °C(Predicted)
• Appearance: /
• Density: 1.220±0.06 g/cm3(Predicted)
• PKA: 4.83±0.10(Predicted)
• CAS DataBase Reference: 1H-Tetrazole,5-[(4-ethoxyphenyl)methyl]-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole,5-[(4-ethoxyphenyl)methyl]-(9CI)(132372-78-2)
• EPA Substance Registry System: 1H-Tetrazole,5-[(4-ethoxyphenyl)methyl]-(9CI)(132372-78-2)

Safety Data

• Hazardous Substances Data: 132372-78-2(Hazardous Substances Data)

Upstream product

• 6775-77-5 4-ethoxyphenylacetonitrile 

Downstream Products

• 1283134-72-4 2,3,4,6-tetra-O-acetyl-1-{5-[(4-ethoxyphenyl)methyl]-1H-tetrazol-1-yl}-1-deoxy-β-D-galactopyranose 
• 1283134-66-6 2,3,4,6-tetra-O-acetyl-1-{5-[(4-ethoxyphenyl)methyl]-2H-tetrazol-2-yl}-1-deoxy-β-D-galactopyranose 
• 1283134-71-3 2,3,4,6-tetra-O-acetyl-1-{5-[(4-ethoxyphenyl)methyl]-1H-tetrazol-1-yl}-1-deoxy-β-D-glucopyranose 
• 1186641-44-0 2,3,4,6-tetra-O-acetyl-1-{5-[(4-ethoxyphenyl)methyl]-2H-tetrazol-2-yl}-1-deoxy-β-D-glucopyranose 
• 132372-95-3 [5-(4-Ethoxy-benzyl)-tetrazol-2-yl]-acetic acid 
• 132372-86-2 [5-(4-Ethoxy-benzyl)-tetrazol-1-yl]-acetic acid 

Relevant articles and documents

Design, synthesis and in vivo hypoglycemic activity of tetrazole-bearing N-glycosides as SGLT2 inhibitors

Novel tetrazole-bearing N-glycosides have been designed and synthesized as SGLT2 inhibitors via a conventional protocol starting from substituted phenylacetic acids and two monosaccharides, D-glucose and D-galactose, and their hypoglycemic activity has been tested in vivo by mice oral glucose tolerance test (OGTT). Two compounds are found to be more potent than the positive control Dapagliflozin. The structure-activity relationship has also been investigated.