132373-48-9Relevant academic research and scientific papers
SYNTHESIS AND PROPERTIES OF DERIVATIVES OF 7-AROYLALKYLXANTHINYL-8-THIOACETIC ACID
Garmash, S. N.,Skul'skaya, E. A.,Priimenko, B. A.,Klyuev, N. A.
, p. 807 - 811 (2007/10/02)
When 7-aroylalkyl-8-bromo-3-methyl- and -1,3-dimethylxanthines are boiled with an excess of thioglycolic acid, a reductive dehalogenation takes place, while reaction with an equimolar amount of thioglycolic acid in DMFA leads to 7-aroylalkyl-3-methyl- and -1,3-dimethylxanthinyl-8-thioacetic acids.Cyclization of the latter with acetic anhydride in the presence of anhydrous sodium acetate results in the formation of 3-aryl-1,4-dihydro-9-methyl- and -7,9-dimethylthiazinoxanthine.
