132382-74-2

Upstream product

• 18997-19-8 Chloromethyl pivalate 
• 132382-56-0 (E)-(R)-5-Phenylacetylamino-hex-3-enoic acid 
• 132382-53-7 N-((E)-(R)-1-Methyl-5-trimethylsilanyl-pent-2-en-4-ynyl)-2-phenyl-acetamide 
• 127043-29-2 N-((R)-1-Methyl-2-oxo-ethyl)-2-phenyl-acetamide 

Relevant academic research and scientific papers

SYNTHESIS AND STABILITY OF FUNCTIONALIZED EPOXIDES TOPOLOGICALLY RELATED TO β-LACTAM ANTIBIOTICS

Epoxides 3-4 topologically related to penicillins and oxamazins have been designed as potential alkylating inhibitors of bacterial D,D-peptidases.A series of N-acylated olefins 17-19 and 22 have been prepared.It was found that the corresponding epoxides bearing a free carboxyl group were unstable.Neither the olefinic precursors nor the lactones 23 resulting from ring opening of the epoxides 4 exhibited any antibacterial activity.