132391-25-4

Upstream product

• 617-35-6 2-oxo-propionic acid ethyl ester 
• 99-61-6 3-nitro-benzaldehyde 
• 98253-69-1 2-(trimethylsilyloxy)acrylic acid ethyl ester 
• 3395-79-7 m-nitrobenzaldehyde dimethylacetal 

Downstream Products

• 845961-02-6 2-amino-3-cyano-6-ethoxycarbonyl-4H-4-(m-nitrophenyl)pyran 
• 1225464-81-2 C₁₉H₂₁NO₇ 
• 1301224-25-8 C₁₇H₁₉NO₇ 
• 1301224-27-0 C₁₇H₁₉NO₆S 
• 1301224-23-6 C₁₈H₂₁NO₆ 
• 1361926-27-3 ethyl (S)-4-methyl-2-oxo-4-(m-nitrophenyl)but-3-enoate 
• 1375648-59-1 ethyl 4-(3-nitrophenyl)-2-oxo-4-(1H-pyrazol-1-yl)butanoate 
• 1350721-99-1 (R,Z)-1-(ethoxycarbonyl)-4-nitro-3-(3-nitrophenyl)but-1-enyl benzoate 

Relevant academic research and scientific papers

Enantioselective copper-catalyzed conjugate addition of trimethylaluminium to β,γ-unsaturated α-ketoesters

Not a cop out: The copper-catalyzed asymmetric conjugate addition of organometallic reagents to Michael acceptors is an important methodology for forming a C-C bond in an enantioselective manner. Such an addition of Me 3Al to β,γ-unsaturated α-

Synthesis and antimicrobial activity of new polyfunctionally substituted pyridines and their fused derivatives

Ethyl pyruvate (EP) on reacting with malononitrile or isothiocyanates gives the pyridine derivatives 5 and 9a, b, respectively. Chalcone derivative of EP reacts with malononitrile to yield the pyran derivative which in turn is transformed into pyridine derivative 14. Reactivity of 5 and 9a towards different organic reagents has been investigated. Antimicrobial activity of some newly synthesized pyridines is also reported.