1323947-62-1Relevant academic research and scientific papers
Iridium-Catalyzed [2+2+2] Cycloaddition of α,ω-Diynes with Cyanamides
Hashimoto, Toru,Ishii, Satoshi,Yano, Reiko,Miura, Hiroki,Sakata, Ken,Takeuchi, Ryo
, p. 3901 - 3916 (2015)
The complex [Ir(cod)Cl]2/DPPF or rac-BINAP is an efficient catalyst for the [2+2+2] cycloaddition of α,ω-diynes with cyanamides. A wide range of cyanamides derived from secondary amines are good coupling partners for α,ω-diynes. The reaction of
Iron-catalyzed cycloaddition reaction of diynes and cyanamides at room temperature
Wang, Chunxiang,Wang, Dongping,Xu, Fen,Pan, Bin,Wan, Boshun
, p. 3065 - 3072 (2013/06/27)
An iron-catalyzed [2 + 2 + 2] cycloaddition reaction of diynes and cyanamides at room temperature is reported. Highly substituted 2-aminopyridines were obtained in good to excellent yields with high regioselectivity. Insights toward the reaction process w
Iron-catalyzed formation of 2-aminopyridines from diynes and cyanamides
Lane, Timothy K.,D'Souza, Brendan R.,Louie, Janis
, p. 7555 - 7563 (2012/11/07)
Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This system was also used to cyclize two terminal alkynes and
Nickel-catalyzed [2+2+2] cycloaddition of diynes and cyanamides
Stolley, Ryan M.,MacZka, Michael T.,Louie, Janis
, p. 3815 - 3824 (2011/09/16)
A variety of bicyclic N,N-disubstituted 2-aminopyridines have been prepared from diynes and cyanamides by nickel-catalyzed [2+2+2] cycloaddition reactions. The reactions proceeded at room temperature with low catalyst loading to afford 2-aminopyridines in
