1324004-41-2Relevant academic research and scientific papers
Synthesis of pyrimidine-containing nucleoside β-(R/S)- hydroxyphosphonate analogues
Meurillon, Maia,Chaloin, Laurent,Perigaud, Christian,Peyrottes, Suzanne
, p. 3794 - 3802 (2011)
A concise route to nucleoside β-hydroxyphosphonate analogues is described. The use of a nucleoside β-ketophosphonate as the key intermediate allowed both the (R) and (S) isomers of β-hydroxyphosphonate analogues in the pyrimidine series to be accessed. Such derivatives may be considered as stable mimics of 5′-monophosphate nucleosides and, therefore, could be the starting point for the development of potential therapeutic agents. Copyright
Gold(I)-catalyzed reactions of propargyl esters with vinyl derivatives
Sperger, Christian A.,Tungen, Jorn E.,Fiksdahl, Anne
supporting information; experimental part, p. 3719 - 3722 (2011/09/12)
A gold-catalyzed olefin cyclopropanation reaction of propargyl esters with vinyl ester or vinyl sulfonamide derivatives was investigated for the synthesis of highly substituted cyclopropane derivatives in good diastereoselectivity. By varying the vinyl sp
